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Low dose and fast grating-based x-ray phase-contrast imaging using the integrating-bucket phase modulation technique

机译:基于低剂量和快速光栅的X射线相位对比成像   积分桶相位调制技术

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摘要

X-ray phase-contrast imaging has experienced rapid development over the lastfew decades, and in this technology, the phase modulation strategy ofphase-stepping is used most widely to measure the sample's phase signal.However, because of its discontinuous nature, phase-stepping has the defects ofworse mechanical stability and high exposure dose, which greatly hinder itswide application in dynamic phase measurement and potential clinicalapplications. In this manuscript, we demonstrate preliminary research on theuse of integrating-bucket phase modulation method to retrieve the phaseinformation in grating-based X-ray phase-contrast imaging. Experimental resultsshowed that our proposed method can be well employed to extract thedifferential phase-contrast image, compared with the current mostly usedphase-stepping strategy, advantage of integrating-bucket phase modulationtechnique is that fast measurement and low dose are promising.
机译:X射线相衬成像技术在过去的几十年中经历了飞速发展,在这项技术中,相位步进的相位调制策略被广泛用于测量样品的相位信号。但是,由于其不连续性,相位步进具有机械稳定性差和暴露剂量高的缺点,极大地阻碍了其在动态相位测量中的广泛应用和潜在的临床应用。在本文中,我们演示了使用积分桶式相位调制方法检索基于光栅的X射线相衬成像中的相位信息的初步研究。实验结果表明,本文提出的方法可以很好地提取差分相位差图像,与目前最常用的相位步进策略相比,集成桶相位调制技术的优点是测量速度快,剂量低。

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